The Zephyr makes the journey from New Madrid to New Orleans in late 1861. A year later, the Zephyr reaches Cairo, Illinois, and is greeted by Union gunboats. The war is now on the water, and there is little room for river commerce.
When Cory learns that a Union force under Ulysses S. Grant is advancing toward the forts to claim the area for the North, Cory and his crewmates must choose sides and join in the fight to see which side will control the river.